Singles
2008 Masters Series Monte-Carlo
Final
Champion	Rafael Nadal
Runner-up	Roger Federer
Score	7–5, 7–5
Details
Draw	56 (7 Q / 4 WC )
Seeds	16
Events
Singles Doubles
← 2007 · Masters Series Monte-Carlo · 2009 →

Three-time defending champion Rafael Nadal defeated Roger Federer in a rematch of the previous two years' finals, 7–5, 7–5 to win the singles tennis title at the 2008 Monte-Carlo Masters. For the second year in a row, he did not lose a single set in the entire tournament.

The top eight seeds receive a bye into the second round.

	Quarterfinals							Semifinals							Final
	1	Roger Federer	5	6	6
	6	David Nalbandian	7	2	2
								1	Roger Federer	6	3
								3	Novak Djokovic	3	2r
	3	Novak Djokovic	6	6
		Sam Querrey	4	0
															1	Roger Federer	5	5
															2	Rafael Nadal	7	7
		Igor Andreev	3	6	5
	4	Nikolay Davydenko	6	4	7
								4	Nikolay Davydenko	3	2
								2	Rafael Nadal	6	6
	5	David Ferrer	1	5
	2	Rafael Nadal	6	7

	First round							Second round							Third round							Quarterfinals
								1	R Federer	6	3	77
	Q	R Ramírez Hidalgo	6	6				Q	R Ramírez Hidalgo	1	6	61
		G Simon	1	1											1	R Federer	6	6
		G Monfils	7	6												G Monfils	3	4
		F Verdasco	5	4					G Monfils	710	6
		S Grosjean	6	4	1r			15	I Karlović	68	1
	15	I Karlović	4	6	4																	1	R Federer	5	6	6
	12	T Robredo	6	7																		6	D Nalbandian	7	2	2
		S Wawrinka	4	5				12	T Robredo	6	77
		R Štěpánek	4	78	3				R Söderling	4	63
		R Söderling	6	66	6										12	T Robredo	1	0
		T Haas	1	0r											6	D Nalbandian	6	6
	Q	O Rochus	6	3				Q	O Rochus	4	3
								6	D Nalbandian	6	6

	First round							Second round							Third round							Quarterfinals
								3	N Djokovic	6	6
	WC	G Kuerten	1	2					I Ljubičić	3	3
		I Ljubičić	6	6											3	N Djokovic	6	6
		N Mahut	2	3											14	A Murray	0	4
		F Volandri	6	6					F Volandri	4	1
		F López	65	4				14	A Murray	6	6
	14	A Murray	77	6																		3	N Djokovic	6	6
	10	C Moyá	3	6	3																		S Querrey	4	0
		S Querrey	6	1	6				S Querrey	6	7
		A Calleri	4	3					A Seppi	1	5
		A Seppi	6	6												S Querrey	2	6	6
		F Santoro	64	1											7	R Gasquet	6	4	3
	Q	K Vliegen	77	6				Q	K Vliegen	1	2
								7	R Gasquet	6	6

	First round							Second round							Third round							Quarterfinals
								8	M Youzhny	3	r
		I Andreev	7	6					I Andreev	6
		D Tursunov	5	3												I Andreev	7	4	6
		N Almagro	6	6												N Almagro	5	6	4
	WC	J-R Lisnard	4	4					N Almagro	6	3
		H-t Lee	0	5				11	J Mónaco	2	0r
	11	J Mónaco	6	7																			I Andreev	3	6	5
	16	P Kohlschreiber	77	6																		4	N Davydenko	6	4	7
		J Acasuso	64	3				16	P Kohlschreiber	6	6
		M Čilić	6	64	3				N Kiefer	2	4
		N Kiefer	3	77	6										16	P Kohlschreiber	6	5	2
		JI Chela	2	2											4	N Davydenko	3	7	6
	Q	S Bolelli	6	6				Q	S Bolelli	2	65
								4	N Davydenko	6	77

	First round							Second round							Third round							Quarterfinals
								5	D Ferrer	6	6
	WC	M Safin	6	6				WC	M Safin	2	3
		X Malisse	3	2											5	D Ferrer	6	6
	Q	N Lapentti	77	62	6											J Tipsarević	4	0
		P Starace	63	77	4			Q	N Lapentti	7	65	4
		J Tipsarević	6	2	6				J Tipsarević	5	77	6
	9	P-H Mathieu	4	6	3																	5	D Ferrer	1	5
	13	JC Ferrero	67	6	6																	2	R Nadal	6	7
		M Llodra	79	1	1			13	JC Ferrero	6	6
		J Nieminen	6	6					J Nieminen	3	3
	Q	M Gicquel	0	4											13	JC Ferrero	4	1
	Q	I Minář	3	4											2	R Nadal	6	6
	WC	M Ančić	6	6				WC	M Ančić	0	3
								2	R Nadal	6	6

• Draw
• Qualifying draw