The 2006 Bucknell Bison football team was an American football team that represented Bucknell University during the 2006 NCAA Division I FCS football season. It tied for fourth in the Patriot League.

Bucknell played its home games at Christy Mathewson–Memorial Stadium on the university campus in Lewisburg, Pennsylvania.

In its fourth season under head coach Tim Landis, the Bison compiled a 6–5 record.^[1] Stefan Niemczyk and Dorian Petersen were the team captains.^[2]

The Bison were outscored 268 to 222. Their 3–3 conference record tied with Colgate for fourth place in the seven-team Patriot League standings.^[3]

Date	Opponent	Site	Result	Attendance	Source
September 2	at Duquesne*	Christy Mathewson–Memorial Stadium Lewisburg, PA	W 31–28 OT	1,910	[4]
September 9	No. 25 Lafayette	Christy Mathewson–Memorial Stadium Lewisburg, PA	L 0–31	6,273	[5]
September 16	Cornell*	Christy Mathewson–Memorial Stadium Lewisburg, PA	W 20–5	6,152	[6]
September 23	at No. 7 Richmond*	University of Richmond Stadium Richmond, VA	L 21–48	4,900	[7]
September 30	at Marist*	Leonidoff Field Poughkeepsie, NY	W 48–19	2,417	[8]
October 7	Penn*	Christy Mathewson–Memorial Stadium Lewisburg, PA	L 24–34	6,250	[9]
October 14	at Georgetown	Multi-Purpose Field Washington, DC	W 17–7		[1]
October 21	at Lehigh	Goodman Stadium Bethlehem, PA	L 7–38	10,673	[10]
October 28	Fordham^	Christy Mathewson–Memorial Stadium Lewisburg, PA	W 13–3	4,792	[11]
November 4	at Holy Cross	Fitton Field Worcester, MA	L 10–27	5,126	[12]
November 18	Colgate	Christy Mathewson–Memorial Stadium Lewisburg, PA	W 31–28		[1]
*Non-conference game Homecoming ^ Parents Weekend Rankings from The Sports Network Poll released prior to the game