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Hepatocit

Hepatocit
(Hepatocytus)
Hepatocit i krvni sud (sinusoid) jetre pacova.
Poprečni presjek ljudske jetre.
Identifikatori
CodeTH H3.04.05.0.00006
THH3.04.05.0.00006
FMA14515
Anatomska terminologija

Hepatociti su specijalizirane ćelije tkiva jetre, koji čine oko 70-80% ukupne jetrene mase.[1][2][3][4]

Glavne funkcije hepatocita su:

Hepatociti takođe iniciraju formiranje i sekreciju žuči.[5][6][7]

Histologija

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Hepatociti imaju eozinofilnu citoplazmu, što je posljedica prisustva brojnih mitohondrija i bazofilni izgled usljed velikih količina hrapavog endoplazmatskg retikuluma i slobodnih ribosoma. U poodmaklim godinama, također su uočkljiva i smeđa lipofuskinska zrnca, zajedno sa neregularnim neobojenim oblastima citoplazme. Bogate su citoplazmatskim glikogenom i lipidnim slojevima koji su otklonjeni tokom histološke pripreme. Prosječno trajanje hepatocita je oko pet mjeseci. Poznato je da imaju veliku moć regeneracije.[8]

Također pogledajte

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Reference

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  1. ^ Sofradžija A., Šoljan D., Hadžiselimović R. (2003): Biologija 1, Svjetlost, Sarajevo, ISBN 9958-10-592-6.
  2. ^ Hadžiselimović R., Pojskić N. (2005): Uvod u humanu imunogenetiku. Institut za genetičko inženjerstvo i biotehnologiju (INGEB), Sarajevo, ISBN 9958-9344-3-4.
  3. ^ Bajrović K, Jevrić-Čaušević A., Hadžiselimović R., Ed. (2005): Uvod u genetičko inženjerstvo i biotehnologiju. Institut za genetičko inženjerstvo i biotehnologiju (INGEB), Sarajevo, ISBN 9958-9344-1-8.
  4. ^ Maurel P. (2010): Hepatocytes: Methods and protocols. Humana Press, ISBN 1607616874.
  5. ^ Patrick Maurel (2010). Hepatocytes: Methods and Protocols (Methods in Molecular Biology) (1st Ed. izd.). Humana Press. ISBN 1607616874. |edition= sadrži dodatni tekst (pomoć)
  6. ^ Hughes, Robin D. (2009). Anil Dhawan (ured.). Hepatocyte Transplantation: Methods and Protocols (Methods in Molecular Biology) (1 edition izd.). Humana Press. ISBN 1588298833. |edition= sadrži dodatni tekst (pomoć)
  7. ^ Growth, Proliferation, and Apoptosis of Hepatocytes (1 ed. izd.). Springer. 2001. ISBN 4431703233. Nepoznati parametar |edtor= zanemaren (pomoć); |edition= sadrži dodatni tekst (pomoć)
  8. ^ Međedović S., Maslić E., Hadžiselimović R. (2000): Biologija 2. Svjetlost, Sarajevo, ISBN 9958-10-222-6.

Literatura

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  • Growth, Proliferation, and Apoptosis of Hepatocytes (1 ed. izd.). Springer. 2001. ISBN 4431703233. Nepoznati parametar |edtor= zanemaren (pomoć); |edition= sadrži dodatni tekst (pomoć)CS1 održavanje: ref=harv (link)
  • Hughes, Robin D. (2009). Anil Dhawan (ured.). Hepatocyte Transplantation: Methods and Protocols (Methods in Molecular Biology) (1 edition izd.). Humana Press. ISBN 1588298833. |edition= sadrži dodatni tekst (pomoć)CS1 održavanje: ref=harv (link)
  • Patrick Maurel (2010). Hepatocytes: Methods and Protocols (Methods in Molecular Biology) (1st Ed. izd.). Humana Press. ISBN 1607616874. |edition= sadrži dodatni tekst (pomoć)CS1 održavanje: ref=harv (link)

Vanjski linkovi

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Hepatocit
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