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Autosomno nasljeđivanje

Autosomno nasljeđivanje podrazumijeva da fenotipsko ispoljavanje određenog svojstva zavisi od prisustva ili odsustva odgovarajućih alela sa autosoma. Osobina, tj. njena fenotipska varijanta može biti dominantna ili recesivna, a javlja se podjednako često u oba spola. Većina nasljednih bolesti i poremećaja su posljedica oštećenih gena na autosomima, što je i očekivano, imajući u vidu njihov broj i veličinu, tj. njihov relativni udio u genomu.[1][2][3][4][5]

Na osnovu prirode interakcije među odgovornim alelima razlikujemo:

  • Autosomno dominantno nasljeđivanje,
  • Autosomno nepotpuno dominantno (intermedijarno) nasljeđivanje i
  • Autosomno recesivno nasljeđivanje.

Postoji još i kategorija rijetkih karaktera koji imaju

  • Pseudoautosomno nasljeđivanje:
    • Dominantno i
    • Recesivno.[6]

Reference

[uredi | uredi izvor]
  1. ^ Campbell N. (2005). Biology. Benjamin/ Cummings, San Francisco ISBN 0-07-366175-9.
  2. ^ Hadžiselimović R., Pojskić N. (2005): Uvod u humanu imunogenetiku. Institut za genetičko inženjerstvo i biotehnologiju (INGEB), Sarajevo, ISBN 9958-9344-3-4.
  3. ^ King R. C., Stransfield W. D. (1998): Dictionary of genetics. Oxford niversity Press, New York, Oxford, ISBN 0-19-50944-1-7; ISBN 0-19-509442-5.
  4. ^ Hadžiselimović R. (2005): Bioantropologija – Biodiverzitet recentnog čovjeka. Institut za genetičko inženjerstvo i biotehnologiju (INGEB), Sarajevo, ISBN 9958-9344-2-6.
  5. ^ Lincoln R. J., Boxshall G. A. (1990): Natural history - The Cambridge illustrated dictionary. Cambridge University Press, Cambridge, ISBN 0 521 30551-9.
  6. ^ Hartl D., Jones E. (2005): Genetics: Analysis of genes and genomes, 6th Edition, Jones & Bartlett, New York, ISBN 0-7637-1511-5.

Također pogledajte

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Autosomno nasljeđivanje
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