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موپیروسین

موپیروسین
Structural formula of mupirocin
Ball-and-stick model of the mupirocin molecule
کلینیک معلوماتلاری
تیجارت آدلاریBactroban, others
سینونیم‌لرmuciprocin[۱]
ای‌اچ‌اف‌اس/Drugs.comMonograph
مدلاین‌پلاسa688004
ایجازه معلوماتلاری
حامیله‌لیک
کتیقوریاسی
  • AU: B1
  • US: B (No risk in non-human studies)
ایستیفاده
مئتودو		Topical, nasal
ای‌تی‌سی کودو
حوقوقی وضعیت
حوقوقی وضعیت
  • AU: S4 (Prescription only)
  • US: ℞-only
فارماکوکینتیک معلوماتلار
Protein binding97%
Elimination half-life20 to 40 minutes
تانیملایجیلار
IUPAC name
  • 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
سی‌ای‌اس نومره‌سی
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard100.106.215 بونو ویکی‌دئیتادا دییشدیر
شیمیایی و فیزیکی معلوماتلار
فورمولC26H44O9
مول جرمی500.622 g/mol
۳دی مودلی (جی‌مول)
SMILES
  • O=C(O)CCCCCCCCOC(=O)\C=C(/C)C[C@@H]2OC[C@H](C[C@@H]1O[C@H]1[C@@H](C)[C@@H](O)C)[C@@H](O)[C@H]2O
InChI
  • InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1 YesY
  • Key:MINDHVHHQZYEEK-HBBNESRFSA-N YesY
 NYesY (بو نه‌دیر؟)  (تصدیق ائتمک)

موپیروسین (آیوپاک آدی: 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-, اینگیلیسجه: Mupirocin, (چینجه:莫匹罗星‎)، عربجه: موبيروسين، روسجا: Мупироцин) بیر شیمیایی بیلشیک دواء. بۇ دواءنین مول جرمیسی مول/قرم ۵۰۰٫۶۲۲ دیر. موپیروسین آنتی‌بیوتیک‌ اۆچون ایستیفاده اوْلونور.

بیرده باخ

[دَییشدیر]

قایناقلار

[دَییشدیر]
  1. ^ Fleischer, Alan B. (2002). Emergency Dermatology: A Rapid Treatment Guide (in انگلیسی). McGraw Hill Professional. p. 173. ISBN 9780071379953. 2017-09-10-ده اوریجنال-دن آرشیولشدیریلمیشدیر. ((cite book)): |archive-date= / |archive-url= وقت مؤهورونون اۇیغونسوزلوغو (کؤمک); Unknown parameter |deadurl= ignored (|url-status= suggested) (کؤمک)
  • اینگلیسیجه ویکی پدیا

ائشیک باغلانتی‌لار

[دَییشدیر]

قارداش پروژه‌لرده موپیروسین گؤره داها آرتیق بیلگی‌لر تاپابیلرسینیز.

Search Commons فایل‌لار ویکی‌آمباردا


Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)
30S
Aminoglycosides
(initiation inhibitors)
-mycin (Streptomyces)
  • Paromomycin
-micin (Micromonospora)
  • Verdamicin
  • Astromicin
Tetracycline antibiotics
(tRNA binding)
Tetracyclines
Glycylcyclines
  • Tigecycline
Fluorocyclines
  • Eravacycline†
50S
Oxazolidinone
(initiation inhibitors)
Peptidyl transferase
Amphenicols
Pleuromutilins
  • Retapamulin
  • Tiamulin
  • Valnemulin
MLS (transpeptidation/translocation)
Macrolides
Lincosamides
Streptogramins
  • Pristinamycin
  • Quinupristin/dalfopristin
  • Virginiamycin
EF-G
Steroid antibacterials
  • #WHO-EM
  • ‡بازاردان چیخاریلیب
  • کلینیک سیناقلار:
    • †فاز III
    • §III فازا هئچ وقت
آنتی‌بیوتیک‌ active on the cell wall and envelope (J01C-J01D)
Intracellular
Glycopeptide
β-lactams/
(inhibit PBP
cross-links)
پنی‌سیلینs
(Penams)
Narrow
spectrum
β-lactamase sensitive
(1st generation)
  • بنزیل پنی‌سیلین#
  • Benzathine benzylpenicillin#
  • Procaine benzylpenicillin#
  • Phenoxymethylpenicillin (V)#
  • Propicillin‡
  • Pheneticillin‡
  • Azidocillin‡
  • Clometocillin‡
  • Penamecillin‡
β-lactamase resistant
(2nd generation)
Extended
spectrum
Aminopenicillins (3rd generation)
Carboxypenicillins (4th generation)
Ureidopenicillins (4th generation)
Other
  • Mecillinam‡ (Pivmecillinam‡)
  • Sulbenicillin‡
Penems
  • Faropenem‡
  • Ritipenem§
Carbapenems
Cephalosporins
/ Cephamycins
(Cephems)
1st generation
2nd generation
  • Cefaclor
  • سيفوتيتان
  • Cephamycin (Cefoxitin
  • Cefprozil
  • سفوروکسیم
  • Cefuroxime axetil
  • Cefamandole‡
  • Cefminox‡
  • Cefonicid‡
  • Ceforanide‡
  • Cefotiam‡
  • Cefbuperazone‡
  • Cefuzonam‡
  • Cefmetazole)‡
  • Carbacephem‡ (Loracarbef‡)
3rd generation
4th generation
  • سفپیم
  • Cefozopran‡
  • Cefpirome‡
  • Cefquinome‡
5th generation
  • Ceftaroline fosamil
  • Ceftolozane
  • Ceftobiprole
Veterinary
  • Ceftiofur
  • Cefquinome
  • Cefovecin
Monobactams
β-lactamase inhibitors
  • Penam (Sulbactam
  • Tazobactam)
  • Clavam (Clavulanic acid)
  • Avibactam
  • Vaborbactam†
Combinations
  • کوآموکسی‌کلاو#
  • Imipenem/cilastatin#
  • Ampicillin/flucloxacillin
  • Ampicillin/sulbactam (Sultamicillin)
  • Ceftazidime/avibactam
  • Piperacillin/tazobactam
  • Ceftolozane/tazobactam
Other
  • #WHO-EM
  • ‡بازاردان چیخاریلیب
  • کلینیک سیناقلار:
    • †فاز III
    • §III فازا هئچ وقت
آنتی‌بیوتیک‌: nucleic acid inhibitors (J01E, J01M)
Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)
DHFR inhibitor
Sulfonamides
(DHPS inhibitor)
Short-
acting
  • Sulfaisodimidine
  • Sulfamethizole
  • Sulfadimidine
  • Sulfapyridine
  • Sulfafurazole
  • Sulfanilamide
  • Sulfathiazole
  • Sulfathiourea
Intermediate-
acting
Long-
acting
  • Sulfadimethoxine
  • Sulfadoxine
  • Sulfalene
  • Sulfametomidine
  • Sulfametoxydiazine
  • Sulfamethoxypyridazine
  • Sulfaperin
  • Sulfamerazine
  • Sulfaphenazole
  • Sulfamazone
Other/ungrouped
Combinations
Other DHPS inhibitors
Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)
1st g.
Fluoro-
quinolones
2nd g.
3rd g.
  • لووفلوکساسین#
  • Balofloxacin‡
  • Grepafloxacin‡
  • Pazufloxacin‡
  • Sparfloxacin‡
  • Temafloxacin‡
  • Tosufloxacin‡
4th g.
Vet.
  • Danofloxacin
  • Difloxacin
  • Enrofloxacin
  • Ibafloxacin
  • Marbofloxacin
  • Orbifloxacin
  • Pradofloxacin
  • Sarafloxacin‡
Newer non-fluorinated
  • Nemonoxacin
Related (DG)
Anaerobic DNA
inhibitors
نیترو ایومیدازول ایومیدازول derivatives
Nitrofuran derivatives
RNA synthesis
Rifamycins/
RNA polymerase
  • #WHO-EM
  • ‡بازاردان چیخاریلیب
  • کلینیک سیناقلار:
    • †فاز III
    • §III فازا هئچ وقت
بؤلمه‌لر
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موپیروسین
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